The project Ambient Amplifiers (2000, Birger Sevaldson, Phu Duong) investigated a series of topics addressing soft programming across scales (from city scale to building scale) as a strategy to introduce systemic synergies between the actors found in the field of the location and to provide flexibility and imagined or unimagined responses to unforeseen future change and activities. This global strategy for the unforeseen was composed out of several means spanning from intentionally planned devices (e.g. a programmable street,) semi-planned devices (the pavilion-islands which could be up and downgraded in pre-designed steps) and devices for unplanned change and use ( the grafted and computer generated geometries that allowed for several interpretation and uses).
Though this project does not explicitly state its relation to systems thinking it is in really characterized by innovative contributions to the field. The most important contribution of the project seen in the context of systems oriented design is that it demonstrates a digital design process based on a composite strategy as a response to flexibility and unforeseen change.
See the web version of the project here >>>>>